| 2025 | Estamos todos en directo con John Mulaney (serie) | Self |
| 2024 | Adam Ray Is Dr. Phil UNLEASHED | Self |
| 2024 | Chain Reactions | Self |
| 2024 | John Mulaney presenta: Estamos todos en Los Ángeles (serie) | Self |
| 2024 | Cazafantasmas: Imperio helado | Dr. Hubert Wartzki |
| 2024 | Manhunt: la caza del asesino (serie) | Det. Lafayette Baker |
| 2024 | After Midnight (serie) | Self |
| 2024 | Grimsburg (serie) | (voice) |
| 2023 | Heroes of the Golden Masks | Aesop (voice) |
| 2023 | Unicorn Boy | King Uniturius (voice) |
| 2022 | Los StoryBots responden (serie) | Super Snowy Icy Cone Guy |
| 2022 | Celebrity Jeopardy! (serie) | Self |
| 2022 | Patton Oswalt: We All Scream | Self |
| 2022 | The Jennifer Hudson Show (serie) | Self |
| 2022 | Dark Side of Comedy (serie) | Self |
| 2022 | MEAD | MEAD (voice) |
| 2022 | I Love My Dad | Chuck |
| 2022 | Sandman (serie) | Matthew the Raven (voice) |
| 2022 | Mike Mignola: Drawing Monsters | Self |
| 2022 | George Carlin's American Dream (serie) | Self |
| 2022 | Gaslit (serie) | Chuck Colson |
| 2021 | La noche del fin de los tiempos | Pyrantin |
| 2021 | Ultrasecretos (serie) | TSA Guard (voice) |
| 2021 | La maldición de Molly McGee (serie) | Mayor Brunson (voice) |
| 2021 | Teenage Euthanasia (serie) | — |
| 2021 | Colonia Pingüino (serie) | Self |
| 2021 | M.O.D.O.K. (serie) | George Tarleton / M.O.D.O.K. (voice) |
| 2021 | Hacks (serie) | Patton Oswalt |
| 2021 | 52 - A Tale of Loneliness | 52 |
| 2020 | A Virtual Princess Bride Reunion | Moderator / Villager |
| 2020 | A Virtual Princess Bride Reunion | Moderator |
| 2020 | The Priest | Father Shauna |
| 2020 | In Deep With Ryan Lochte | Narrator |
| 2020 | Home Movie: The Princess Bride (serie) | Vizzini |
| 2020 | El asesino sin rostro (serie) | Self - Michelle's Husband |
| 2020 | Space Force (serie) | Captain Lancaster |
| 2020 | Patton Oswalt: I Love Everything | Self |
| 2020 | Star Trek: Picard (serie) | Spot 73 (voice) |
| 2019 | Bless the Harts (serie) | Vohnnie Ray Power |
| 2019 | You're Not a Monster (serie) | Invisible Man |
| 2019 | A Little Late with Lilly Singh (serie) | Self |
| 2019 | Tamron Hall (serie) | Invitado especial |
| 2019 | Súper Bridget | Max (voice) |
| 2019 | Adams | Roger |
| 2019 | Lights Out with David Spade (serie) | Self - Panelist |
| 2019 | The Boys (serie) | Patton Oswalt (uncredited) |
| 2019 | Mascotas 2 | Max (voice) |
| 2019 | Lo que hacemos en las sombras (serie) | Patton Oswalt |
| 2018 | Minecraft: Modo Historia (serie) | Jesse (male voice) |
| 2018 | Los Conners (serie) | Don Blansky |
| 2018 | Monster Challenge | Self |
| 2018 | Blark and Son (serie) | Mr. Beal (voice) |
| 2018 | Spy Kids: Misión crucial (serie) | — |
| 2018 | Sex Madness Revealed | Jimmy Morris |
| 2018 | We Brought Back MST3K | Self |
| 2018 | A.P. Bio (serie) | Principal Ralph Durbin |
| 2018 | Comida para Phil (serie) | Self |
| 2017 | Happy! (serie) | Happy (voice) |
| 2017 | Click, Clack, Moo: Christmas at the Farm | Appliance Al (voice) |
| 2017 | Big Hero 6: La serie (serie) | Mr. Sparkle (voice) |
| 2017 | Patton Oswalt: Annihilation | Self |
| 2017 | I Love You, America (serie) | Self |
| 2017 | Will y Grace (serie) | Danley Walker |
| 2017 | Marvel Spider-Man (serie) | Uncle Ben (voice) |
| 2017 | El círculo | Tom Stenton |
| 2017 | Dimension 404 (serie) | Uncle Dusty |
| 2017 | The History of Comedy (serie) | Self |
| 2017 | Santa Clarita Diet (serie) | Dr. Hasmedi |
| 2016 | Laurie Kilmartin: 45 Jokes About My Dead Dad | Self |
| 2016 | Justice League Action (serie) | Space Cabbie (voice) |
| 2016 | Nerdland | Elliot (voice) |
| 2016 | Las apariencias engañan | Bruce Springstein / Scorpion |
| 2016 | Zoolander: Super Model | Dr. Botoxo (voice) |
| 2016 | HarmonQuest (serie) | Sand Pole |
| 2016 | Neil Gaiman: Dream Dangerously | Self |
| 2016 | Lady Dynamite (serie) | Patton Cop |
| 2016 | Patton Oswalt: Talking for Clapping | Self |
| 2016 | The Confirmation | Drake |
| 2016 | Funny or Die presenta: La película del arte de la negociación de Donald Trump | Merv Griffin |
| 2016 | Full Frontal with Samantha Bee (serie) | Self |
| 2015 | Crazy Ex-Girlfriend (serie) | J. Castleman |
| 2015 | The Late Show with Stephen Colbert (serie) | Self |
| 2015 | Welcome to Bridgetown | Self |
| 2015 | Somos osos (serie) | Nom Nom / Additional Voices (voice) |
| 2015 | The Loneliest Stoplight | Narrator (voice) |
| 2015 | Call Me Lucky | Self |
| 2015 | Difficult People (serie) | Kenny Jurgens |
| 2015 | Cerdo, Cabra, Banana, Grillo (serie) | Jimmy Ron Cricket (voice) |
| 2015 | Chronic-Con, Episode 420: A New Dope | Self |
| 2015 | Dude Bro Party Massacre III | Chief |
| 2015 | Battle Creek (serie) | Mayor Hardy |
| 2014 | Sex and Broadcasting | Self |
| 2014 | We the Economy: 20 Short Films You Can't Afford to Miss | Lemonade Stand Dad |
| 2014 | Lemonade War | Jerry |
| 2014 | BoJack Horseman (serie) | Pinky Penguin (voice) |
| 2014 | TripTank (serie) | Pegasus (voice) |
| 2014 | Late Night with Seth Meyers (serie) | Self |
| 2014 | The Tonight Show Starring Jimmy Fallon (serie) | Self |
| 2014 | Off Camera with Sam Jones (serie) | Self |
| 2014 | Patton Oswalt: Tragedy Plus Comedy Equals Time | Self |
| 2013 | La vida secreta de Walter Mitty | Todd Maher |
| 2013 | Radiolab Live: Apocalyptical | Self |
| 2013 | Rick y Morty (serie) | Beta 7 (voice) |
| 2013 | The Walking Dead: A Decade of Dead | Self |
| 2013 | Mighty Med (serie) | Ed / The Extrminator |
| 2013 | Marvel Agentes de S.H.I.E.L.D. (serie) | Billy Koenig / Sam Koenig |
| 2013 | Los Goldberg (serie) | Adam Goldberg (voice) |
| 2013 | Brooklyn Nine-Nine (serie) | Fire Marshall Boone |
| 2013 | The Jeselnik Offensive (serie) | Self |
| 2013 | Odd Thomas, cazador de fantasmas | Ozzie P. Boone |
| 2012 | Viva Lucha Libre | Self |
| 2012 | Comedians in Cars Getting Coffee (serie) | Self |
| 2012 | Gravity Falls (serie) | Franz (voice) |
| 2012 | The Bitter Buddha | Self |
| 2012 | Comedy Bang! Bang! (serie) | Self |
| 2012 | Veep (serie) | Teddy Sykes |
| 2012 | Nature Calls | Randy Stevens |
| 2011 | Billy on the Street (serie) | Self |
| 2011 | Young adult | Matt Freehauf |
| 2011 | The Heart, She Holler (serie) | Hurlan |
| 2011 | Patton Oswalt: Finest Hour | Self |
| 2011 | Portlandia (serie) | Thor83 |
| 2011 | Bob's Burgers (serie) | Moody Foodie (voice) |
| 2010 | Robotomy (serie) | — |
| 2010 | My Little Pony: La magia de la amistad (serie) | Quibble Pants (voice) |
| 2010 | Hope (serie) | Rubin |
| 2010 | Neighbors from Hell (serie) | Pazuzu |
| 2010 | Weird: The Al Yankovic Story | Dr. Demento |
| 2010 | Justified: La ley de Raylan (serie) | Bob Sweeney |
| 2010 | Blood Into Wine | Self |
| 2010 | Caprica (serie) | Baxter Sarno |
| 2009 | Modern Family (serie) | Ducky |
| 2009 | Community (serie) | Male Nurse Jackie |
| 2009 | Archer (serie) | Alan Shapiro (voice) |
| 2009 | Patton Oswalt: My Weakness Is Strong | Self |
| 2009 | Funny People: Live | Self |
| 2009 | Watch What Happens Live with Andy Cohen (serie) | Invitado especial |
| 2009 | Al's Brain | Co-Worker |
| 2009 | Parks and Recreation (serie) | Garth Blundin |
| 2009 | Late Night with Jimmy Fallon (serie) | Invitado especial |
| 2009 | Dollhouse (serie) | Joel Mynor |
| 2009 | Big Fan | Paul Aufiero |
| 2009 | United States of Tara (serie) | Neil |
| 2008 | Lewis Black's Root of All Evil (serie) | Self |
| 2008 | History of the Joke | Self |
| 2008 | Todos los caminos llevan a casa | Milo |
| 2007 | Tu amiga la rata | Remy (voice) |
| 2007 | Super High Me | Self |
| 2007 | Reaper (serie) | — |
| 2007 | The Comedians of Comedy: Live at The Troubadour | Self |
| 2007 | WordGirl (serie) | Tobey McCalister III (voice) |
| 2007 | Comedy Central Roast of Flavor Flav | Self |
| 2007 | Patton Oswalt: Werewolves and Lollipops | Self |
| 2007 | Último aviso (serie) | Calvin Schmidt |
| 2007 | Ratatouille | Remy (voice) |
| 2007 | Flight of the Conchords (serie) | Elton John Impersonator |
| 2007 | The Sophisticated Misfit | Self |
| 2007 | Human Giant (serie) | Let's Go Fan |
| 2007 | Tim and Eric Awesome Show, Great Job! (serie) | Joshua Beard |
| 2007 | The Sarah Silverman Program. (serie) | Vincent Van Guy |
| 2006 | Last Laugh '06 | Self |
| 2006 | The Amazing Screw-On Head | Mr. Groin (voice) |
| 2006 | The Comedians of Comedy: Live at the El Rey | Self |
| 2005 | Comedians of Comedy (serie) | Self |
| 2005 | Cake Boy | Cake Pervert |
| 2005 | The Comedians of Comedy | Self |
| 2005 | Padre made in USA (serie) | Candy Maker (voice) |
| 2004 | Patton Oswalt: No Reason to Complain | Self |
| 2004 | Tom Goes to the Mayor (serie) | Zynx (voice) |
| 2004 | Squidbillies (serie) | Talking Squid (voice) |
| 2004 | Veronica Mars (serie) | Penn Epner |
| 2004 | The Batman (serie) | Marty Slack (voice) |
| 2004 | The Venture Bros. (serie) | Wonderboy (voice) |
| 2004 | No te la pierdas | Felix |
| 2004 | Best Week Ever (serie) | — |
| 2003 | Dos hombres y medio (serie) | Billy Stanhope |
| 2003 | Comedy Central Roasts (serie) | Self |
| 2003 | Reno 911! (serie) | — |
| 2003 | Real Time with Bill Maher (serie) | Self |
| 2003 | Jimmy Kimmel Live! (serie) | Self |
| 2002 | Kim Possible (serie) | Professor Dementor (voice) |
| 2001 | Los padrinos mágicos (serie) | Crimson Chin Writer |
| 2000 | Aqua Teen Hunger Force (serie) | — |
| 2000 | Larry David (serie) | Harry Baskin |
| 2000 | Descarga estática (serie) | Specs (voice) |
| 1999 | Home Movies (serie) | — |
| 1999 | Futurama (serie) | Unattractive Giant Monster (voice) |
| 1999 | Padre de familia (serie) | Bear Show Manager (voice) |
| 1999 | Batman del futuro (serie) | Eldon Michaels (voice) |
| 1998 | Comedy Central Presents (serie) | — |
| 1998 | El rey de Queens (serie) | Spence Olchin |
| 1997 | The Weird Al Show (serie) | Seymour |
| 1997 | Emeril Live (serie) | — |
| 1996 | The Daily Show (serie) | Self |
| 1995 | MADtv (serie) | Crip in Wheelchair |
| 1995 | Dr. Katz, Professional Therapist (serie) | Patton (voice) |
| 1995 | NewsRadio (serie) | Guy |
| 1994 | HBO Comedy Half Hour (serie) | Self |
| 1993 | Late Night with Conan O'Brien (serie) | Invitado especial |
| 1992 | The Tonight Show with Jay Leno (serie) | — |
| 1989 | Los Simpson (serie) | T-Rex (voice) / Bart's guilt (voice) |
| 1989 | Seinfeld (serie) | Clerk |
