| 2024 | Ezra | Jayne |
| 2024 | Leopardi & Co | Mildred |
| 2024 | Atrabilious | Dr. Andrea Hart |
| 2023 | Oprah: Viaje hacia el Color Púrpura | Self |
| 2023 | Three Trees | (Narration) |
| 2023 | Our Barbara -- A Special Edition of 20/20 | Self |
| 2022 | 20/20 Presents Black Panther: In Search of Wakanda | Self |
| 2022 | Till, el crimen que lo cambió todo | Alma |
| 2022 | Music Is My Life - Joseph Shabalala and Ladysmith Black Mambazo | Self |
| 2022 | Cuomo (serie) | Invitado especial |
| 2022 | Sherri (serie) | Invitado especial |
| 2022 | Cinderella: The Reunion, A Special Edition of 20/20 | Self |
| 2022 | Luck | Captain (voice) |
| 2022 | Tony Bennett: Forget Me Not | Self |
| 2022 | Whoopi Goldberg: The Winning Act | Self (archive footage) |
| 2022 | JANET JACKSON. (serie) | Self |
| 2021 | Harlem (serie) | Dr. Elise Pruitt |
| 2021 | JFK: Destiny Betrayed (serie) | Self - Narrator (voice) |
| 2021 | JFK: Caso revisado | Self - Narrator (voice) |
| 2021 | The Center Seat: 55 Years of Star Trek (serie) | Self |
| 2021 | The Most Magical Story on Earth: 50 Years of Walt Disney World | Self - Host |
| 2021 | Rita Moreno: una chica que decidió ir a por todas | Self |
| 2021 | M.O.D.O.K. (serie) | Marian Pouncy / Poundcakes (voice) |
| 2021 | Hacks (serie) | Whoopi Goldberg |
| 2021 | The Story of Late Night (serie) | Self |
| 2021 | 50 años de Barrio Sésamo | Self - Guest |
| 2020 | The Stand (serie) | Abagail "Mother Abagail" Freemantle |
| 2020 | Walter Winchell: The Power of Gossip | Narrator |
| 2020 | The Con (serie) | Narrator (voice) |
| 2020 | Staged (serie) | Mary |
| 2020 | The Sit-In: Harry Belafonte Hosts The Tonight Show | Self |
| 2020 | Find Your Groove | Self |
| 2020 | Star Trek: Picard (serie) | Guinan |
| 2019 | El padrino de Harlem (serie) | Miss Willa |
| 2019 | The Most Magnificent Thing | Narrator (voice) |
| 2019 | Cracked Up: The Darrell Hammond Story | Self |
| 2019 | Tamron Hall (serie) | Invitado especial |
| 2019 | El programa de Kelly Clarkson (serie) | Self |
| 2019 | Scooby Doo y compañía (serie) | Whoopi Goldberg (voice) |
| 2019 | Anfibilandia (serie) | Mother Olm (voice) |
| 2019 | Charley Pride: I'm Just Me | Self |
| 2018 | The Rolling Stones - Voodoo Lounge Uncut | Self - Host |
| 2018 | De tonta, nada | Lola |
| 2018 | Basketball: A Love Story (serie) | Self (archive footage) |
| 2018 | The Shop (serie) | Self |
| 2018 | Random Acts of Flyness (serie) | Police Officer |
| 2018 | Campamento Mágico (serie) | Barb (voice) |
| 2018 | La historia de la ciencia ficción (serie) | Self |
| 2018 | El evangelio según André Leon Talley | Self |
| 2018 | El permiso | Moms |
| 2018 | Mister Rogers: It's You I Like | Self |
| 2018 | Citizen Rose (serie) | Self |
| 2017 | Decorating Disney: Holiday Magic | Host |
| 2017 | Sammy Davis, Jr.: I've Gotta Be Me | Self |
| 2017 | Yamasong: March of the Hollows | Yari |
| 2017 | 9/11 | Metzie |
| 2017 | Los 90 (serie) | Self (archive footage) |
| 2017 | The Truth Is in the Stars | Self |
| 2017 | A Very Sordid Wedding | Abernatha Coleman |
| 2017 | When We Rise (serie) | Pat Norman |
| 2017 | King of the Dancehall | Loretta Brixton |
| 2016 | Do I Look Like a Lady? (Comedians and Singers) | Self (archive footage) |
| 2016 | La hora de Tufo y Pringue (serie) | Meg (voice) |
| 2016 | La Garrapata (serie) | Whoopi Goldberg |
| 2016 | Pregunta a los StoryBots (serie) | — |
| 2015 | The Late Show with Stephen Colbert (serie) | Self |
| 2015 | Black Dog, Red Dog | Calliope |
| 2015 | The Three Stooges: Hey Moe! Hey Dad! | Self |
| 2015 | De magie van het dagboek van Anne Frank | Self |
| 2015 | StarTalk with Neil deGrasse Tyson (serie) | Self |
| 2015 | Misery Loves Comedy | Self |
| 2014 | Soltera a los 40 | Fleeta Mullins |
| 2014 | BoJack Horseman (serie) | Mikhaela (voice) |
| 2014 | The 7D (serie) | Magic Mirror (voice) |
| 2014 | Demasiado tarde para perdonar | Viola |
| 2014 | Late Night with Seth Meyers (serie) | Self |
| 2014 | The Tonight Show Starring Jimmy Fallon (serie) | Self |
| 2014 | Broad City (serie) | Self |
| 2013 | Kelly Clarkson's Cautionary Christmas Music Tale | Self |
| 2013 | Érase una vez en el País de las Maravillas (serie) | Mrs. Rabbit (voice) |
| 2013 | Richard Pryor: Omit the Logic | Self |
| 2013 | Moms Mabley | Self |
| 2013 | Why We Laugh: Funny Women | Self |
| 2013 | The Contradictions of Fair Hope | Narrator |
| 2012 | Paul Simon. Under African Skies | Self |
| 2011 | Being Elmo: A Puppeteer's Journey | Narrator (voice) |
| 2011 | Suburgatory (Fuera de lugar) (serie) | Yakult (voice) |
| 2011 | La pequeña locomotora que sí pudo | The Tower (voice) |
| 2011 | Un pedacito de cielo | God |
| 2011 | Bubble Guppies (serie) | Pirate Myra (voice) |
| 2010 | Familia de policías (serie) | Regina Thomas |
| 2010 | The Black List: Volume Three | Self |
| 2010 | RuPaul: Reinas del drag: ¡Desatadas! (serie) | Invitado especial |
| 2010 | See You in September | Lindsay's Therapist (uncredited) |
| 2009 | The Middle (serie) | Jane Marsh |
| 2009 | Watch What Happens Live with Andy Cohen (serie) | Invitado especial |
| 2009 | Journey to the Stars | Narrator (voice) |
| 2009 | Glee (serie) | Carmen Tibideaux |
| 2009 | The Captain's Summit | Self |
| 2009 | Late Night with Jimmy Fallon (serie) | Self |
| 2009 | RuPaul: Reinas del drag (serie) | Self - Special Guest |
| 2008 | Los Teleñecos en Navidad: Cartas a Santa Claus | Taxi Driver |
| 2008 | Shatner's Raw Nerve (serie) | Self |
| 2008 | Descendants | Red Flower (voice) |
| 2008 | Meerkat Manor: The Story Begins | Self - Narrator (voice) |
| 2007 | The Sophisticated Misfit | Self |
| 2007 | Elton 60: Live at Madison Square Garden | Self |
| 2007 | Ghost Stories: The Making of a Classic | Self |
| 2007 | The Graham Norton Show (serie) | Self |
| 2007 | The Naked Brothers Band (serie) | Herself |
| 2007 | If I Had Known I Was a Genius | Mom |
| 2006 | Comic Relief 2006 | — |
| 2006 | Rockefeller Plaza (serie) | Whoopi Goldberg |
| 2006 | Rachael Ray (serie) | — |
| 2006 | Homie Spumoni | Thelma |
| 2006 | The One Show (serie) | Invitado especial |
| 2006 | So NoTORIous (serie) | — |
| 2006 | Doogal | Ermintrude (voice) |
| 2006 | The N Word | Herself |
| 2005 | The Reichen Show (serie) | Self |
| 2005 | Todo el mundo odia a Chris (serie) | — |
| 2005 | Kathy Griffin: My Life on the D-List (serie) | Self |
| 2005 | Pesadilla en la cocina (serie) | Self - Restaurant Patron |
| 2005 | Whoopi Goldberg: Back to Broadway | Herself / Fontaine / Lurleen / Crippled Lady |
| 2004 | The Tony Danza Show (serie) | Invitado especial |
| 2004 | The World of Nat King Cole | Self |
| 2004 | P3K: Pinocho 3000 | Cyberina (voice) |
| 2004 | Uta Hagen's Acting Class | Self |
| 2003 | Whoopi (serie) | Mavis Rae |
| 2003 | The Ellen DeGeneres Show (serie) | Self |
| 2003 | New Jersey Devils Stanley Cup 2002-2003 Champions | Voice |
| 2003 | Declaration of Independence | Self |
| 2003 | Real Time with Bill Maher (serie) | Self |
| 2003 | Unchained Memories: Readings from the Slave Narratives | Narrator (voice) |
| 2003 | Jimmy Kimmel Live! (serie) | — |
| 2003 | Las buenas relaciones | Mabel Spader |
| 2003 | Richard Pryor: I Ain't Dead Yet!! | Self |
| 2002 | Mi querida Madeline | Miss Clavel (voice) |
| 2002 | Liberty's Kids (serie) | (voice) |
| 2002 | Dawn French's Girls Who Do Comedy (serie) | — |
| 2001 | The Making of 'A Charlie Brown Christmas' | Self - Hostess |
| 2001 | Llámame Santa Claus | Lucy Cullins |
| 2001 | Ley y orden: Acción criminal (serie) | Chesley Watkins |
| 2001 | Tramposos en Hollywood | Woman at Funeral (uncredited) |
| 2001 | Ratas a la carrera | Vera Baker |
| 2001 | Ghost: Remembering the Magic | Self |
| 2001 | Golden Dreams | Califia, the Queen of California |
| 2001 | Corazon al descubierto | Terry Harrison |
| 2000 | The Weber Show (serie) | Whoopi Goldberg |
| 2000 | Mary Pickford: A Life on Film | Self - Host / Narrator |
| 2000 | Doctoras de Filadelfia (serie) | Dr. Lydia Emerson |
| 2000 | Mas perros que huesos | Cléo |
| 2000 | Here's to You, Charlie Brown: 50 Great Years | Self - Host |
| 1999 | La leyenda mágica de los Leprechauns (serie) | The Grand Banshee |
| 1999 | Ley y orden: Unidad de Víctimas Especiales (serie) | Janette Grayson |
| 1999 | The Foxbusters (serie) | Ransome (voice) |
| 1999 | Jackie's Back! | Nurse Ethyl Washington Rue Owens (Jackie's Sister) |
| 1999 | En lo profundo del océano | Candy Bliss |
| 1999 | Alegría: An Enchanting Fable | Baby Clown |
| 1999 | Billy Connolly: Erect for 30 Years | — |
| 1999 | Get Bruce! | Self |
| 1998 | Rugrats: La Película | Ranger Margaret (voice) |
| 1998 | Desmadre en Camelot | Dr. Vivien Morgan |
| 1998 | Rudolph, el reno de la nariz roja | Stormella (voice) |
| 1998 | Cómo Stella recuperó la marcha | Delilah Abraham |
| 1998 | Titey | The Iceberg (voice) |
| 1998 | Celebrity Deathmatch (serie) | — |
| 1998 | ¡Arde Hollywood! | Whoopi Goldberg |
| 1997 | A Christmas Carol | Spirit of Christmas Present (voice) |
| 1997 | El oso de la casa azul (serie) | Edwina Badger (voice) |
| 1997 | Mother Goose: A Rappin' and Rhymin' Special | Mother Gooseberg (voice) |
| 1997 | Pitch | Herself |
| 1997 | The View (serie) | Self - Co-Host |
| 1997 | Destination Anywhere | Cabbie |
| 1997 | Al caer la noche | Nurse Myrna |
| 1997 | Classic Albums (serie) | Self (archive footage) |
| 1997 | The Chris Rock Show (serie) | — |
| 1996 | Fantasmas del pasado | Myrlie Evers |
| 1996 | Cómo triunfar en Wall Street | Laurel Ayres |
| 1996 | Bogus | Harriet Franklin |
| 1996 | The Rosie O'Donnell Show (serie) | Invitado especial |
| 1996 | Eddie | Eddie Franklin |
| 1996 | The Good, The Bad, and the Beautiful | Self (archive footage) |
| 1996 | Muppets Tonight (serie) | Self |
| 1996 | El celuloide oculto | Self |
| 1995 | Dino Rex | Katie Coltrane |
| 1995 | The Rolling Stones: Voodoo Lounge | Self - Hostess |
| 1995 | MADtv (serie) | Self |
| 1995 | Mujeres bajo la luna | Sylvie Morrow |
| 1995 | Dr. Katz, Professional Therapist (serie) | Whoopi (voice) |
| 1995 | Happily Ever After: Fairy Tales for Every Child (serie) | Mother Gooseberg (voice) |
| 1995 | Sólo ellas... los chicos a un lado | Jane Deluca |
| 1994 | The Making of 'The Pagemaster' | Self (archive footage) |
| 1994 | El Guardián de las Palabras | Fantasy (voice) |
| 1994 | Inside the Actors Studio (serie) | Self |
| 1994 | Corina, Corina | Corrina Washington |
| 1994 | But... Seriously | Self (archive footage) |
| 1994 | Sesame Street: The Best of Elmo | Self |
| 1993 | A Cool Like That Christmas | Mom / Irwin (voice) |
| 1993 | Sister Act 2: De vuelta al convento | Deloris Van Cartier |
| 1993 | La niñera (serie) | Edna |
| 1993 | Late Night with Conan O'Brien (serie) | Invitado especial |
| 1993 | Aretha Franklin: Duets | Self |
| 1993 | Made in America | Sarah Mathews |
| 1992 | Sarafina! | Mary Masembuko |
| 1992 | Wisecracks | — |
| 1992 | Sister Act (Una monja de cuidado) | Deloris Van Cartier / Sister Mary Clarence |
| 1992 | The Tonight Show with Jay Leno (serie) | — |
| 1992 | El juego de Hollywood | Detective Avery |
| 1992 | Defenders of Dynatron City | Ms. Megawatt (voice) |
| 1991 | Chez Whoopi | Self - Host |
| 1990 | El largo camino a casa | Odessa Cotter |
| 1990 | El Capitán Planeta y los Planetarios (serie) | Gaia (voice) |
| 1990 | Ghost (Más allá del amor) | Oda Mae Brown |
| 1990 | Bagdad Cafe (serie) | Brenda |
| 1990 | Celebrity Guide to Wine | Self |
| 1989 | Whoopi Goldberg Presents Billy Connolly | Herself |
| 1989 | Homer y Eddie | Eddie Cervi |
| 1989 | Historias de la cripta (serie) | Peligre |
| 1989 | El sabor del dinero | Sarah Collins |
| 1989 | Comic Relief III | — |
| 1988 | Free to Be... a Family | Self |
| 1988 | El desafío de una mujer | Clara Mayfield |
| 1988 | This Morning (serie) | Self |
| 1988 | Whoopi Goldberg's Fontaine... Why Am I Straight? | Fontaine |
| 1988 | The Nelson Mandela 70th Birthday Concert | Self |
| 1987 | Belleza mortal | Rita Rizzoli |
| 1987 | Star Trek: La nueva generación (serie) | Guinan |
| 1987 | Dolly (serie) | Self |
| 1987 | A Different World (serie) | Dr. Jordan |
| 1987 | Happy 100th Birthday, Hollywood | Self |
| 1987 | Scared Straight!: 10 Years Later | Self - Host |
| 1987 | La ratera | Bernice 'Bernie' Rhodenbarr |
| 1987 | Carol, Carl, Whoopi and Robin | — |
| 1987 | The Pointer Sisters: Up All Nite | Self |
| 1986 | The Best of Comic Relief | Self |
| 1986 | Cómo se hizo el Capitán EO | Host |
| 1986 | American Masters (serie) | Self |
| 1986 | Bob Goldthwait -- Don't Watch This Show | — |
| 1986 | Jumpin' Jack Flash | Terry Dolittle |
| 1986 | Doctor Duck's Super Secret All-Purpose Sauce | Self |
| 1985 | El color púrpura | Celie |
| 1985 | Whoopi Goldberg: Direct from Broadway | Self |
| 1985 | Luz de luna (serie) | Camille Brand |
| 1984 | Los Pequeñecos (serie) | — |
| 1982 | Wogan (serie) | Self |
| 1982 | Citizen | — |
| 1981 | Wetten, dass..? (serie) | Self |
| 1975 | Saturday Night Live (serie) | Self - Cameo (uncredited) |
| 1973 | The American Film Institute Salute to ... (serie) | Self |
| 1971 | Great Performances (serie) | Self |
| 1953 | The Oscars (serie) | Self |
| -0001 | Saturday TV Funhouse (serie) | Iceberg (voice) |
