| 2024 | 765874: Unification | Kirk |
| 2024 | The D-Con Chamber (serie) | Self |
| 2024 | The UnXplained: Mysteries of the Universe (serie) | Self - Presenter |
| 2024 | William Shatner: You Can Call Me Bill | Self |
| 2024 | Masters del Universo: Revolución (serie) | Keldor (voice) |
| 2023 | The UnXplained Special Presentation (serie) | Self - Presenter |
| 2023 | Full Moon's Roadshow Revisited | Self (archive footage) |
| 2023 | Stars on Mars (serie) | Self - Host |
| 2022 | Sunday with Laura Kuenssberg (serie) | Self |
| 2022 | A Tear in the Sky | — |
| 2022 | Piers Morgan Uncensored (serie) | Self |
| 2022 | Fireheart | Mayor of New York (voice) |
| 2021 | Shatner in Space | Self |
| 2021 | Expedition Unknown: Shark Trek | Self |
| 2021 | WWE Hall Of Fame 2020 | Himself |
| 2021 | Senior Moment | Victor Martin |
| 2020 | Creators: The Past | Lord Oghma |
| 2019 | Hasta tu última muerte | The Overseer (voice) |
| 2019 | Devil's Revenge | Hayes |
| 2019 | El programa de Kelly Clarkson (serie) | Self |
| 2019 | Lo inexplicable (serie) | Self - Host |
| 2019 | My Life Is Murder (serie) | Barton Wallwork |
| 2019 | Mask Singer: Adivina quién canta (Estados Unidos) (serie) | Knight (archive footage) |
| 2018 | Star Trek: Short Treks (serie) | Capt. James T. Kirk (voice) (archive footage) |
| 2018 | The Steam Engines of Oz | Oscar "Oz" Diggs (voice) |
| 2018 | Aliens Ate My Homework | Phillogenus esk Piemondum (Phil) (voice) |
| 2017 | The Indian Detective (serie) | David Marlowe |
| 2017 | Batman Vs. Dos Caras | Harvey Dent / Two-Face (voice) |
| 2017 | The Truth Is in the Stars | Self |
| 2016 | Unlocked: The World of Games, Revealed (serie) | Self |
| 2016 | Por el amor de Spock | Self |
| 2016 | Better Late Than Never (serie) | Self |
| 2016 | When Elephants Were Young | Narrator |
| 2016 | Range 15 | Richard Chindler |
| 2016 | Private Eyes (serie) | Norm Glinski |
| 2016 | They Came from the Swamp: The Films of William Grefé | Himself (voice only) |
| 2016 | A Sunday Horse | Kenneth Roubidoux |
| 2016 | The Colorful Montreal Expos | Narrator (voice) |
| 2015 | Justo a Tiempo para Navidad | Coachman Nick |
| 2015 | Being Canadian | Self |
| 2015 | A Christmas Horror Story | Dangerous Dan |
| 2015 | StarTalk with Neil deGrasse Tyson (serie) | Self |
| 2015 | Tom Felton Meets the Superfans | Self |
| 2014 | A Star Is Drawn: Rob Simone's Look Inside Comic-Con | Self |
| 2014 | Chaos on the Bridge | Self |
| 2014 | To Be Takei | Self |
| 2014 | Last Week Tonight with John Oliver (serie) | Self |
| 2014 | La verdadera historia de la ciencia ficción (serie) | Self |
| 2013 | The Captains Close Up (serie) | Self |
| 2013 | Still Kicking | Himself |
| 2012 | Gotham Comedy Live (serie) | Self - Host |
| 2012 | Horrorween | Himself |
| 2012 | Get a Life! | Himself |
| 2012 | Comic Book Men (serie) | Self |
| 2011 | Comedy Central Roast of Charlie Sheen | Self - Roaster |
| 2011 | William Shatner Sings O Canada | Himself |
| 2011 | The Captains | Himself |
| 2011 | The Space Shuttle | Narrator |
| 2011 | Billy Blackburn's Treasure Chest: Rare Home Movies and Special Memories | — |
| 2011 | Life Beyond Trek: William Shatner | — |
| 2010 | The Fran Drescher Show (serie) | — |
| 2010 | The Talk (serie) | — |
| 2010 | My Little Pony: La magia de la amistad (serie) | Grand Pear (voice) |
| 2010 | Aftermath with William Shatner (serie) | Self - Host |
| 2010 | Haven (serie) | Croatoan |
| 2010 | Rookie Blue (serie) | Henry McLeod |
| 2010 | Póquer de reinas (serie) | Sally |
| 2010 | Weird or What? (serie) | — |
| 2009 | William Shatner's Gonzo Ballet | Himself |
| 2009 | The Captain's Summit | Self |
| 2008 | Hay que pillar a Papá Noel | Santa Claus (voice) |
| 2008 | Shatner's Raw Nerve (serie) | Self - Host |
| 2008 | Everest (serie) | Norman Kelly |
| 2008 | Los misterios de Murdoch (serie) | Mark Twain |
| 2008 | Extraordinary Animals (serie) | — |
| 2007 | Rumbo a Marte (serie) | Narrator (voice) |
| 2007 | Big Bang (serie) | William Shatner |
| 2006 | Comedy Central Roast of William Shatner | Self |
| 2006 | Psych (serie) | Frank O'Hara |
| 2006 | Vecinos invasores | Ozzie (voice) |
| 2006 | Salvaje (The Wild) | Kazar (voice) |
| 2006 | The Henry Rollins Show (serie) | — |
| 2006 | Stalking Santa | Narrator |
| 2006 | William Shatner in Concert | Self |
| 2006 | 40 Years of Star Trek | Self |
| 2005 | How William Shatner Changed The World | Self - Host / Narrator (voice) |
| 2005 | The Reichen Show (serie) | Invitado especial |
| 2005 | The Colbert Report (serie) | — |
| 2005 | Pesadilla en la cocina (serie) | Self |
| 2005 | Invasion Iowa (serie) | Col. Shane Yeager |
| 2005 | Miss Agente Especial 2: Armada y fabulosa | Stan Fields |
| 2005 | Lil' Pimp | Tony Gold (voice) |
| 2005 | The Late Late Show with Craig Ferguson (serie) | Self |
| 2004 | Boston Legal (serie) | Denny Crane |
| 2004 | Betty Atómica (serie) | Jim |
| 2004 | The Tony Danza Show (serie) | Invitado especial |
| 2004 | The Rose Parade: A Pageant for the Ages | Self |
| 2004 | Best Week Ever (serie) | — |
| 2004 | Kiss 'N' Tell: Romance in the 23rd Century | — |
| 2004 | Sci-Fi Visionaries | — |
| 2003 | A Carol Christmas | Dr. Bob / Ghost of Christmas Present |
| 2003 | Christmas in Hollywood | Self (archive footage) |
| 2003 | The Ellen DeGeneres Show (serie) | Self |
| 2003 | Chilly Beach (serie) | The President |
| 2003 | Comedy Central Roasts (serie) | Self |
| 2003 | Real Time with Bill Maher (serie) | Self |
| 2003 | Jimmy Kimmel Live! (serie) | Self |
| 2002 | Spplat Attack | — |
| 2002 | Groom Lake | John Gossner |
| 2002 | American Psycho 2: El Legado De Patrick Bateman | Robert Starkman |
| 2002 | After They Were Famous (serie) | Self |
| 2002 | Showtime | William Shatner |
| 2002 | Odisea Cosmica (serie) | — |
| 2002 | Shoot or Be Shot! | Harvey Wilkes |
| 2002 | Star Wars vs. Star Trek: The Rivalry Continues | Self |
| 2001 | Mind Meld: Secrets Behind the Voyage of a Lifetime | Himself |
| 2001 | Gahan Wilson's The Kid | Professor |
| 2001 | Whale Shark Hunters of the Philippines | Self |
| 2001 | Bob Patterson (serie) | Warren Wellman |
| 2001 | Good Day Live (serie) | Self |
| 2001 | Osmosis Jones | Mayor Phlegmming (voice) |
| 2001 | Proyecto Falcon | Major Robert Carson |
| 2001 | Remembering 'The Intruder' | Himself |
| 2001 | NASA: A Space Odyssey Vol. 1 | Narrator |
| 2001 | NASA: A Space Odyssey Vol. 2 | Narrator |
| 2001 | NASA: A Space Odyssey Vol. 3 | Narrator |
| 2000 | Miss Agente Especial | Stan Fields |
| 2000 | Atomic Journeys: Welcome to Ground Zero | Narrator (Voice) |
| 2000 | Click (serie) | Self |
| 1999 | The Late Late Show with Craig Kilborn (serie) | Invitado especial |
| 1999 | Futurama (serie) | William Shatner (voice) |
| 1999 | A Twist in the Tale (serie) | — |
| 1999 | Nukes in Space | Narrator |
| 1998 | Hollywood Ghost Stories | Himself |
| 1998 | Free Enterprise | Bill |
| 1997 | Jefftowne | Himself |
| 1997 | The View (serie) | Self |
| 1997 | Perversions of Science (serie) | Admiral Kornfeld |
| 1997 | El abogado (serie) | Denny Crane |
| 1996 | The Prisoner of Zenda, Inc. | Michael Gatewick |
| 1996 | E! True Hollywood Story (serie) | Self |
| 1996 | Muppets Tonight (serie) | Self |
| 1996 | Dead Man's Island | Chase Prescott |
| 1996 | Cosas De Marcianos (serie) | Big Giant Head |
| 1995 | Trinity and Beyond: The Atomic Bomb Movie | Narrator |
| 1995 | William Shatner's Star Trek Memories | Host |
| 1994 | TekWar (serie) | Walter H. Bascom |
| 1994 | Janek: The Silent Betrayal | Bodosh |
| 1994 | Science Fiction: A Journey Into the Unknown | — |
| 1994 | Star Trek: A Captain's Log | Himself/Host |
| 1994 | William Shatner: Captain's Log | Self |
| 1994 | TekWar: TekJustice | Walter H. Bascom |
| 1994 | El fantasma del Espacio de costa a costa (serie) | — |
| 1994 | TekWar: TekLab | Walter H. Bascom |
| 1994 | TekWar: TekLords | Walter H. Bascom |
| 1994 | TekWar | Walter H. Bascom |
| 1994 | UFO Cover-Up Live with Larry King | Self |
| 1993 | Late Night with Conan O'Brien (serie) | Invitado especial |
| 1993 | SeaQuest DSV (serie) | Milos Tezlof |
| 1993 | Family of strangers | Earl |
| 1993 | Con el arma a punto | General Mortars |
| 1993 | Raw (serie) | — |
| 1993 | Your Guide to Star Trek: Generations | Self |
| 1992 | Eek! The Cat (serie) | Santa Claus (voice) |
| 1992 | The Larry Sanders Show (serie) | William Shatner |
| 1992 | The Tonight Show with Jay Leno (serie) | — |
| 1991 | Aquel país desconocido | Captain James T. Kirk |
| 1991 | Star Trek: 25th Anniversary Special | Self - Host |
| 1990 | El príncipe de Bel-Air (serie) | Himself |
| 1990 | Sigue soñando (serie) | — |
| 1990 | Amazon: Land of the Flooded Forest | Narrator |
| 1989 | Star Trek V: La última frontera | Captain James T. Kirk |
| 1989 | Rescue 911 (serie) | Self - Host |
| 1988 | The Star Trek Saga: From One Generation to the Next | Self |
| 1988 | LIVE with Kelly and Mark (serie) | — |
| 1988 | Broken Angel | Chuck Coburn |
| 1986 | Misión: Salvar La Tierra | Admiral James T. Kirk |
| 1986 | William Shatner's Mysteries of the Way We Feel | Host |
| 1986 | Super Duper Bloopers | Himself |
| 1985 | North Beach and Rawhide | Rawhide MacGregor |
| 1985 | The Ray Bradbury Theater (serie) | Charles Underhill |
| 1985 | Star Trek: The Menagerie | James T. Kirk |
| 1985 | The Canadian Conspiracy | — |
| 1984 | Chantaje a un marido | Chris Jordan |
| 1984 | Star Trek III: En busca de Spock | Admiral James T. Kirk |
| 1982 | Star Trek II: La ira de Khan | Admiral James T. Kirk |
| 1982 | Angustia en el Hospital Central | Gary Baylor |
| 1982 | T. J. Hooker (serie) | Sgt TJ Hooker |
| 1982 | Police Squad! (serie) | Poisoned Man |
| 1982 | Late Night with David Letterman (serie) | Self |
| 1980 | El secuestro del presidente | Jerry O'Connor |
| 1980 | Hypnosis and Beyond | Himself |
| 1979 | Star Trek: La película | Admiral James T. Kirk |
| 1979 | Desastre en el tren de la costa | Stuart Peters |
| 1978 | The Crash of Flight 401 | Carl Tobias |
| 1978 | Land of No Return | Curt Benell |
| 1978 | The Third Walker | Munro Maclean |
| 1977 | The Oregon Trail (serie) | — |
| 1977 | Tarántula | Dr. Robert 'Rack' Hansen |
| 1977 | La conquista del oeste (serie) | Captain Harrison |
| 1976 | A Whale of a Tale | Jack Fredericks |
| 1976 | The Tenth Level | Prof. Stephen Turner |
| 1976 | Perilous Voyage | Steve Monroe |
| 1976 | El mensaje de los dioses | Host |
| 1976 | Microworld | — |
| 1975 | Saturday Night Live (serie) | Self - Cameo (uncredited) |
| 1975 | The Star Trek Dream | Self |
| 1975 | Barbary Coast (serie) | Jeff Cable |
| 1975 | La lluvia del diablo | Mark Preston |
| 1974 | Una mamá sin freno | William J. Baxter |
| 1974 | Kodiak (serie) | Buzz Howard |
| 1974 | La mujer policia (serie) | — |
| 1974 | Petrocelli (serie) | Adam North |
| 1974 | Pray for the Wildcats | Warren Summerfield |
| 1974 | El hombre de los seis millones de dólares (serie) | Josh Lang |
| 1974 | Flick Flack (serie) | Host |
| 1974 | Indict and Convict | Sam Belden |
| 1973 | Pioneer Woman | John Sergeant |
| 1973 | Star Trek: La serie animada (serie) | James T. Kirk (voice) |
| 1973 | Police Story (serie) | — |
| 1973 | The Horror at 37,000 Feet | Paul Kovalik |
| 1973 | Barnaby Jones (serie) | Phil Carlyle / Fred Williams |
| 1973 | Go Ask Alice | Sam |
| 1973 | Incident on a Dark Street | Deaver G. Wallace |
| 1972 | The Rookies (serie) | — |
| 1972 | El sabueso de los Baskerville | George Stapleton |
| 1972 | Hogar perdido | Dr. Curtis |
| 1972 | The Sixth Sense (serie) | — |
| 1971 | Colombo (serie) | Fielding Chase |
| 1971 | Vanished (serie) | Dave Paulick |
| 1970 | The Andersonville Trial | Col. Chipman |
| 1970 | Sole Survivor | Lt. Col. Josef Gronke |
| 1969 | Shadow Game | — |
| 1968 | The Name of the Game (serie) | Peter |
| 1968 | Hawaii 5-0 (serie) | Sam Tolliver |
| 1968 | Comanche blanco | Johnny Moon / Notah |
| 1968 | Alexander The Great | Alexander |
| 1967 | Mannix (serie) | Adam Langer |
| 1967 | Ironside (serie) | — |
| 1966 | CBS Playhouse (serie) | — |
| 1966 | Star Trek: The Menagerie | Captain James T. Kirk |
| 1966 | Incubus | Marc |
| 1966 | Misión: imposible (serie) | Joseph Conrad |
| 1966 | Star Trek (serie) | James T. Kirk |
| 1965 | The F.B.I. (serie) | Arthur Majors |
| 1965 | The Big Valley (serie) | Brett |
| 1964 | Cuatro confesiones | Preacher |
| 1964 | El agente de CIPOL (serie) | — |
| 1963 | La hora de los famosos (serie) | — |
| 1963 | El agente Burke (serie) | Arthur Reynolds |
| 1963 | Channing (serie) | Tom Ericson |
| 1963 | El fugitivo (serie) | Tony Burrell |
| 1963 | Más allá del límite (serie) | Gen. Jeff Barton |
| 1963 | Arrest and Trial (serie) | Larry Tavener |
| 1962 | The Tonight Show Starring Johnny Carson (serie) | Self |
| 1962 | El Intruso (The Intruder) | Adam Cramer |
| 1961 | The Mike Douglas Show (serie) | Self |
| 1961 | The Explosive Generation | Peter Gifford |
| 1961 | Dr. Kildare (serie) | Dr. Carl Noyes |
| 1961 | El show de Dick Powell (serie) | Eric Tegman |
| 1961 | Los defensores (serie) | Assistant District Attorney Earl Rhodes |
| 1960 | Route 66 (serie) | — |
| 1960 | Insight (serie) | Mike Burnett |
| 1960 | Outlaws (serie) | — |
| 1960 | Thriller (serie) | Gil Thrasher |
| 1960 | Police Surgeon (serie) | Joe Flatt |
| 1959 | La dimensión desconocida (serie) | Don Carter |
| 1959 | City Out of Time | Narrator (voice) |
| 1959 | Un paso al más allá (serie) | Carl Bremer |
| 1958 | 77 Sunset Strip (serie) | Paul DeVinger |
| 1958 | Naked City (serie) | Maung Tun |
| 1958 | A Town Has Turned to Dust | Jerry Paul |
| 1958 | Los hermanos Karamazov | Alexi Karamazov |
| 1957 | Las cuatro en punto (serie) | Eli |
| 1957 | The Defender (Studio One) | Kenneth Preston |
| 1955 | Alfred Hitchcock presenta (serie) | John Crane |
| 1955 | Gunsmoke (serie) | Fred Bateman |
| 1954 | Climax! (serie) | Ben Tate |
| 1953 | The Oscars (serie) | Self |
| 1951 | Hallmark Hall of Fame (serie) | Philo |
| 1951 | The Butler's Night Off | — |
| 1948 | Studio One (serie) | Dr. David Coleman |
| 1948 | The Ed Sullivan Show (serie) | Self |
| 1947 | Kraft Television Theatre (serie) | — |
| 1944 | Premios Globo de Oro (serie) | Self - Presenter |
